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Pharmaceutical Intermediates Dehydroepiandrosterone Acetate For Nutritional Supplements

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Pharmaceutical Intermediates Dehydroepiandrosterone Acetate For Nutritional Supplements

Brand Name : Shuangbojie
Model Number : 853-23-6;1239-31-2
Certification : ISO,SGS
Place of Origin : China
MOQ : 10G
Price : Negotiable
Payment Terms : T/T, Western Union, MoneyGram, Bitcoin
Supply Ability : 100KG Per Month
Delivery Time : Within 24 hours after payment confirmed
Packaging Details : As required
MF : C21H30O3
MW : 330.47
EINECS : 212-714-1
Synonyms : Dehydroisoandrosterone 3-acetate
Appearance : White or straw yellow crystalline powder
Standard : Enterprise Standard
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Pharmaceutical Intermediates Dehydroepiandrosterone Acetate For Nutritional Supplements


1) Dehydroepiandrosterone Acetate Details


Name: Dehydroepiandrosterone Acetate
Synonyms: dehydroisoandrosterone 3-acetate; Epiandrosterone Acetate; Prasterone acetate;

Acetate Dehydroepiandrosterone
CAS: 853-23-6;1239-31-2
Molecular Formula:C21H30O3
Molecular Weight: 330.47
EINECS: 212-714-1

Molecular Structure:

Character : White or straw yellow crystalline powder

Quality Standard: Enterprise Standard
Usage: Pharmaceutical intermediates, For the synthesis of steroid hormone drugs. Preparation Products Epiandrosterone acetate-->Methandriol
Packing: foil bag or tin.


2) Dehydroepiandrosterone Acetate Usage


DHEA acetate treatment affected body weight, body composition and utilization of dietary energy by both impairing fat synthesis and promoting fat-free tissue deposition and resting heat production. Possible mechanisms by which DHEA may affect metabolism are discussed.


3) Dehydroepiandrosterone Acetate COA


Test ItemsSpecificationTest Results
DescriptionWhite to almost white crystalline powderConform
Melting point166~170℃167-169℃
Assay≥98.0%99.05%
Impurity≤0.5%0.13%
Loss on drying≤0.5%0.20%

4) Medical Uses


In women with adrenal insufficiency and the healthy elderly there is insufficient evidence to support the use of DHEA.

Menopause
DHEA is sometimes used as an androgen in hormone replacement therapy (HRT) for menopause. A long-lasting ester prodrug of DHEA, prasterone enanthate, is used in combination with estradiol valerate for this indication.

Cancer
There is no evidence DHEA is of benefit in treating or preventing cancer.[20] Although DHEA is postulated as an inhibitor towards glucose-6-phosphate dehydrogenase (G6PD) and suppresses leukemia cell proliferation in vitro, DHEA may enhance G6PD mRNA expression, confounding its inhibitory effects.

Strength
Evidence is inconclusive in regards to the effect of DHEA on strength in the elderly.

In middle-aged men, no significant effect of DHEA supplementation on lean body mass, strength, or testosterone levels was found in a randomized placebo-controlled trial.

Memory
DHEA supplementation has not been found to be useful for memory function in normal middle aged or older adults. It has been studied as a treatment for Alzheimer's disease, but there is no evidence that it is effective.

Cardiovascular disease
A review in 2003 found the then-extant evidence sufficient to suggest that low serum levels of DHEA-S may be associated with coronary heart disease in men, but insufficient to determine whether DHEA supplementation would have any cardiovascular benefit.

Lupus
There is some evidence of short-term benefit in those with systemic lupus erythematosus but little evidence of long-term benefit or safety.

Body composition
A meta-analysis of intervention studies shows that DHEA supplementation in elderly men can induce a small but significant positive effect on body composition that is strictly dependent on DHEA conversion into its bioactive metabolites such as androgens or estrogens.


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6) Our Advantages


1, High quality with competitive price:
1) Standard:BP/USP/EP/Enterprise standard
2) We are manufacturer and can provide high quality products with factory price.

2, Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment.Tracking number available
2) Secure and discreet shipment.Various transportation methods for your choice.
3) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.

3, We have clients throughout the world.
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.


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